Neuropathic Pain
Neuropathic literally means “a dysfunction of the nervous
system”. Physicians use the term “Neuropathic pain” to describe pain that originates from impaired function of the nervous system.
Types of Neuropathic Pain
Neuropathic pain can be divided into central causes (brain and
spinal cord) or peripheral causes (the nerves running from the
spinal cord to the skin) of disruption to the nervous system.
Central causes of neuropathic pain include stroke, traumatic brain
injury, traumatic injury to the spinal cord, multiple sclerosis,
brain tumours, inflammation or infection of the brain or spinal
cord.
Peripheral causes of neuropathic pain are shingles, traumatic
nerve injuries such as brachial plexus avulsions, trigeminal
neuralgia, diabetic neuropathy, alcoholic neuropathy, multiple
sclerosis and amputation. Symptoms
of neuropathic pain.
Neuropathic pain typically causes feelings of burning, electrical
shooting pain, unpleasant tingling, pins and needles, a feeling
of water running down the limb, a crawling feeling beneath the
skin and increased sensitivity to non pain full stimulation (hypersensitivity)
as well as pain to non painfull stimulation (allodynia).
Time
course of Neuropathic Pain
Neuropathic pain does not tend to get better and if it does
it takes a long time to do so. Treatments
- Medication
- Anticonvulsants such as pregablin
or gabapentin
- Tricyclic antidepressants such as
nortriptyline
- Opioids such as morphine
- NMDA receptor antagonists such as
ketamine
- Sodium channel blockers such as
lidocaine
- Canabinoids such as sativex
- Stimulation therapy
- TENS and spinal cord stimulation
- Psychological management
- Coping skills
- Pain management programmes
- as part of a graded exercise programme.
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